Ulo
Topical Minoxidil
Published: January 31, 2026
Video Description
Minoxidil is finally getting its “2.0” upgrade—after 38 years of greasy topicals, irritation, and low response rates, new formulations aim to make it more effective and easier to stick with. In this video I break down SAM-002 (sublingual minoxidil), why standard minoxidil fails so many people, and what you can do right now to maximize results until the Phase 3 data lands in 2026.
High-Strength Minoxidil with Tretinoin, Cetirizine (No PG)
https://ulo.co/discount/MATT15?redirect=/products/topical-minoxidil?variant=42743535992911
Don’t Waste Your Transplant + Money — talk to an expert first:
https://letsgethair.com/consultation
Studies:
https://pmc.ncbi.nlm.nih.gov/articles/PMC10149432/
https://pubmed.ncbi.nlm.nih.gov/31403367/
https://academic.oup.com/ced/article/47/11/1951/6966079
https://pubmed.ncbi.nlm.nih.gov/39688293/
https://pubmed.ncbi.nlm.nih.gov/34420241/
https://onlinelibrary.wiley.com/doi/epdf/10.1111/jdv.20508
https://pmc.ncbi.nlm.nih.gov/articles/PMC10149432/
https://pubmed.ncbi.nlm.nih.gov/24283387/
https://jamanetwork.com/journals/jamadermatology/article-abstract/545803
https://pubmed.ncbi.nlm.nih.gov/33909554/
https://pubmed.ncbi.nlm.nih.gov/40287072/
https://onlinelibrary.wiley.com/doi/10.1111/jocd.15989
https://pubmed.ncbi.nlm.nih.gov/33909554/
Announcements:
https://www.samsonclinical.com/
https://www.prnewswire.com/news-releases/samson-clinical-announces-completion-of-patient-enrolment-into-pivotal-phase-iii-clinical-trial-program-for-sublingual-minoxidil-in-male-pattern-baldness-302615355.html
https://clinicaltrials.gov/study/NCT06924632
Time Stamps
0:00 Intro
0:37 Topical Minoxidil 1.0 (Issues and Challenges)
1:58 Best Topical Minoxidil 1.0 upgrades for max. results
4:05 When to avoid micro-needling
5:08 Minoxidil 10% and 15%
6:58 Minoxidil Sulfate + Liposomal
7:36 Standard oral minoxidil (pros and cons)
9:37 SAM 002 (Minoxidil 2.0)
10:52 SAM 002 - Trial 1b
13:10 SAM 002 Systemic Effects
14:44 SAM 002 - Trial 3 News
15:48 SAM 002 vs VDPHL 01 Comparison
TRANSPARENCY: I’m partnered with Ulo. I only work with companies I believe are a genuinely solid option, though they’re not the only choice. Using my link provides you a discount and supports the work on this channel.
!MEDICAL DISCLAIMER!
Let's Get Hair channel is for general information only, and should not be regarded as a substitute for medical advice from your own doctor or any other health professional.
Let's Get Hair is not a physician and this information should not be construed as medical advice. Always consult your own GP if you’re in any way concerned about your health.